ARG22070
anti-NKG2A + C + E antibody [20d5] (PE)
anti-NKG2A + C + E antibody [20d5] (PE) for Blocking,Flow cytometry and Mouse
概述
| 产品描述 | PE-conjugated Rat Monoclonal antibody [20d5] recognizes NKG2A + C + E |
|---|---|
| 反应物种 | Ms |
| 应用 | BL, FACS |
| 特异性 | Mouse NKG2-A + C + E |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | 20d5 |
| 同位型 | IgG2a, kappa |
| 靶点名称 | NKG2A + C + E |
| 抗原物种 | Mouse |
| 抗原 | CHO cells transfected with B6 allele of NKG2A gene |
| 偶联标记 | PE |
| 別名 | NK cell receptor A; CD159 antigen-like family member A; NKG2-A/NKG2-B type II integral membrane protein; CD159A; CD antigen CD159a; NKG2; NKG2A; NKG2-A/B-activating NK receptor |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | PBS, 0.1% Sodium azide and Sucrose. |
| 抗菌剂 | 0.1% Sodium azide |
| 稳定剂 | Sucrose |
| 浓度 | 0.1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | KLRC1 |
|---|---|
| 全名 | killer cell lectin-like receptor subfamily C, member 1 |
| 背景介绍 | Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jan 2015] |
| 生物功能 | Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. [UniProt] |
| 预测分子量 | 26 kDa |
检测图片 (1) Click the Picture to Zoom In
