ARG66077
anti-NNT1 antibody
anti-NNT1 antibody for ELISA and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NNT1 |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NNT1 |
| 抗原物种 | Human |
| 抗原 | E. coli derived recombinant Human NNT1. (MLNRTGDPGP GPSIQKTYDL TRYLEHQLRS LAGTYLNYLG PPFNEPDFNP PRLGAETLPR ATVDLEVWRS LNDKLRLTQN YEAYSHLLCY LRGLNRQAAT AELRRSLAHF CTSLQGLLGS IAGVMAALGY PLPQPLPGTE PTWTPGPAHS DFLQKMDDFW LLKELQTWLW RSAKDFNRLK KKMQPPAAAV TLHLGAHGF) |
| 偶联标记 | Un-conjugated |
| 別名 | NNT-1; BSF-3; CISS2; Novel neurotrophin-1; NR6; Cardiotrophin-like cytokine factor 1; B-cell-stimulating factor 3; CLC; BSF3; NNT1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9UBD9 Human Cardiotrophin-like cytokine factor 1 |
|---|---|
| 基因名称 | CLCF1 |
| 全名 | cardiotrophin-like cytokine factor 1 |
| 背景介绍 | This gene is a member of the glycoprotein (gp)130 cytokine family and encodes cardiotrophin-like cytokine factor 1 (CLCF1). CLCF1 forms a heterodimer complex with cytokine receptor-like factor 1 (CRLF1). This dimer competes with ciliary neurotrophic factor (CNTF) for binding to the ciliary neurotrophic factor receptor (CNTFR) complex, and activates the Jak-STAT signaling cascade. CLCF1 can be actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. CLCF1 is a potent neurotrophic factor, B-cell stimulatory agent and neuroendocrine modulator of pituitary corticotroph function. Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2). This syndrome is characterized by a profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009] |
| 生物功能 | Cytokine with B-cell stimulating capability. Binds to and activates the ILST/gp130 receptor. [UniProt] |
| 预测分子量 | 25 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG66077 anti-NNT1 antibody standard curve image
Sandwich ELISA: ARG66077 anti-NNT1 antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG66078 anti-NNT1 antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density reading at 405 - 650 nm.
