ARG66737
anti-NSG1 / D4S234E antibody
anti-NSG1 / D4S234E antibody for Western blot and Human,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NSG1 / D4S234E |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NSG1 / D4S234E |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide around the center region of Human NSG1 / D4S234E. |
| 偶联标记 | Un-conjugated |
| 別名 | NEEP21; Neuron-specific protein family member 1; D4S234E; Brain neuron cytoplasmic protein 1; P21; D4S234 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | ~ 23 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.42% Potassium phosphate (pH 7.3), 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 30% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P02683 Rat Neuron-specific protein family member 1 Swiss-port # P42857 Human Neuron-specific protein family member 1 |
|---|---|
| 基因名称 | NSG1 |
| 全名 | neuron specific gene family member 1 |
| 生物功能 | Plays a role in the recycling mechanism in neurons of multiple receptors, including AMPAR, APP and L1CAM and acts at the level of early endosomes to promote sorting of receptors toward a recycling pathway. Regulates sorting and recycling of GRIA2 through interaction with GRIP1 and then contributes to the regulation of synaptic transmission and plasticity by affecting the recycling and targeting of AMPA receptors to the synapse (By similarity). Is required for faithful sorting of L1CAM to axons by facilitating trafficking from somatodendritic early endosome or the recycling endosome (By similarity). In an other hand, induces apoptosis via the activation of CASP3 in response to DNA damage (PubMed:20599942, PubMed:20878061). [UniProt] |
| 细胞定位 | Membrane; Single-pass type II membrane protein. Golgi apparatus, trans-Golgi network membrane. Endosome membrane. Cell projection, dendrite. Early endosome membrane. Late endosome membrane. Lysosome lumen. Recycling endosome membrane. Cytoplasmic vesicle membrane. Golgi apparatus, Golgi stack membrane. Endosome, multivesicular body membrane. Endoplasmic reticulum membrane. [UniProt] |
| 预测分子量 | 21 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG66737 anti-NSG1 / D4S234E antibody WB image
Western blot: CEM, COLO205 and Rat muscle whole cell lysates stained with ARG66737 anti-NSG1 / D4S234E antibody.
