ARG11072
anti-Norepinephrine Transporter antibody [NET-05]
anti-Norepinephrine Transporter antibody [NET-05] for Western blot and Mouse,Rat
概述
| 产品描述 | Mouse Monoclonal antibody [NET-05] recognizes Norepinephrine Transporter |
|---|---|
| 反应物种 | Ms, Rat |
| 不反应物种 | Hu |
| 应用 | WB |
| 特异性 | This antibody recognizes Mouse and Rat NET. It does not recognize Human NET. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | NET-05 |
| 同位型 | IGg2b |
| 靶点名称 | Norepinephrine Transporter |
| 抗原物种 | Mouse |
| 抗原 | KLH-conjugated synthetic peptide around the N-terminal region of Mouse Norepinephrine Transporter. |
| 偶联标记 | Un-conjugated |
| 別名 | SLC6A5; Solute carrier family 6 member 2; NAT1; Norepinephrine transporter; NET; Sodium-dependent noradrenaline transporter; NET1 |
应用说明
| 预测反应性说明 | Sequence homology: Cow (92%); Cat, Human and non-human primate (85%) | ||||
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| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | This antibody is prepared by Ammonium Sulfate precipitation from hybridoma culture media followed by dialysis against PBS. |
| 缓冲液 | PBS and 50% Glycerol. |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O55192 Mouse Sodium-dependent noradrenaline transporter |
|---|---|
| 基因名称 | SLC6A2 |
| 全名 | solute carrier family 6 (neurotransmitter transporter), member 2 |
| 背景介绍 | This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010] |
| 生物功能 | Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals. [UniProt] |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 69 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG11072 anti-Norepinephrine Transporter antibody [NET-05] WB image
Western blot: Mouse cortex homogenate after a 1000xg spin to eliminate non-homegnized tissue fragments of wild type (WT) and NET knockout (NET KO) tissue. The blots were stained with ARG11072 anti-Norepinephrine Transporter antibody [NET-05].
