ARG45192
anti-OTULIN antibody
anti-OTULIN antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes OTULIN |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | OTULIN |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human OTULIN. |
| 偶联标记 | Un-conjugated |
| 別名 | OTULIN; OTU Deubiquitinase With Linear Linkage Specificity; Ubiquitin Thioesterase Otulin; FAM105B; OTU Domain-Containing Deubiquitinase With Linear Linkage Specificity; Family With Sequence Similarity 105, Member B; Deubiquitinating Enzyme Otulin; Ubiquitin Thioesterase Gumby; FLJ34884; EC 3.4.19.12; IMD107; Gumby; AIPDS; GUM |
应用说明
| 应用建议 |
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 43-45 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.01% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | OTULIN |
| 全名 | OTU Deubiquitinase With Linear Linkage Specificity |
| 背景介绍 | This gene encodes a member of the peptidase C65 family of ubiquitin isopeptidases. Members of this family remove ubiquitin from proteins. The encoded enzyme specifically recognizes and removes M1(Met1)-linked, or linear, ubiquitin chains from protein substrates. Linear ubiquitin chains are known to regulate the NF-kappa B signaling pathway in the context of immunity and inflammation. Mutations in this gene cause a potentially fatal autoinflammatory syndrome in human patients. [provided by RefSeq, Sep 2016] |
| 生物功能 | Deubiquitinase that specifically removes linear ('Met-1'-linked) polyubiquitin chains to substrates and acts as a regulator of angiogenesis and innate immune response . [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 40 kDa |
| 翻译后修饰 | Acetylation; Phosphoprotein; Ubl conjugation. [UniProt] |
检测图片 (6) Click the Picture to Zoom In
-
ARG45192 anti-OTULIN antibody IHC-P image
Immunohistochemistry: Human appendicitis stained with ARG45192 anti-OTULIN antibody at 2 μg/ml dilution.
-
ARG45192 anti-OTULIN antibody ICC/IF image
Immunofluorescence: SIHA stained with ARG45192 anti-OTULIN antibody at 5 ug/ml dilution.
-
ARG45192 anti-OTULIN antibody WB image
Western blot: Hela, THP-1, and K562 stained with ARG45192 anti-OTULIN antibody at 0.5 μg/ml dilution.
-
ARG45192 anti-OTULIN antibody FACS image
Flow Cytometry: 293T stained with ARG45192 anti-OTULIN antibody at 1 µg/10^6 cells dilution.
-
ARG45192 anti-OTULIN antibody WB image
Western blot: Rat liver stained with ARG45192 anti-OTULIN antibody at 0.5 μg/ml dilution.
-
ARG45192 anti-OTULIN antibody WB image
Western blot: Mouse liver stained with ARG45192 anti-OTULIN antibody at 0.5 μg/ml dilution.
