ARG64256
anti-PAX6 antibody
anti-PAX6 antibody for Western blot and Mouse
Controls and Markers antibody; Developmental Biology antibody; Gene Regulation antibody; Neuroscience antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes PAX6 |
|---|---|
| 反应物种 | Ms |
| 预测物种 | Hu, Rat |
| 应用 | WB |
| 特异性 | This antibody is expected to recognise both reported isoforms (NP_000271.1 and NP_001595.2). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PAX6 |
| 抗原物种 | Human |
| 抗原 | C-REEKLRNQRRQASN |
| 偶联标记 | Un-conjugated |
| 別名 | MGDA; Aniridia type II protein; AN; Oculorhombin; Paired box protein Pax-6; AN2; WAGR; FVH1; D11S812E |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012] |
| 研究领域 | Controls and Markers antibody; Developmental Biology antibody; Gene Regulation antibody; Neuroscience antibody |
| 预测分子量 | 47 kDa |
| 翻译后修饰 | Ubiquitinated by TRIM11, leading to ubiquitination and proteasomal degradation. |
检测图片 (1) Click the Picture to Zoom In
-
ARG64256 anti-PAX6 antibody WB image
Western Blot: Mouse Eye lysate (35 µg protein in RIPA buffer) stained with ARG64256 anti-PAX6 antibody at 0.5 µg/ml dilution.
