ARG44892
anti-PJA1 antibody
anti-PJA1 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes PJA1 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2b |
| 靶点名称 | PJA1 |
| 抗原物种 | Human |
| 抗原表位 | LEEVREPSLQ EEQASLEEGE IPWLQYHEND SSSEGDNDSG HELMQPGVFM LDGNNNLEDD SSVSEDLEVD WSLFDGFADG LGVAEAISYV DPQFLTYMAL EERLAQAMET ALAHLESLAV DVEVANPPAS KESIDALPEI LVTEDHGAVG QEMCCPICCS EYVKGEVATE LPCHHYFHKP |
| 偶联标记 | Un-conjugated |
| 別名 | PJA1; Praja Ring Finger Ubiquitin Ligase 1; RNF70; PRAJA1; Praja Ring Finger 1, E3 Ubiquitin Protein Ligase; RING-Type E3 Ubiquitin Transferase Praja-1; E3 Ubiquitin-Protein Ligase Praja-1; RING Finger Protein 70; FLJ11830; Praja 1; Praja Ring Finger 1; EC 2.3.2.27; EC 6.3.2; Praja1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8NG27 Human E3 ubiquitin-protein ligase Praja-1 |
|---|---|
| 基因名称 | PJA1 |
| 全名 | Praja Ring Finger Ubiquitin Ligase 1 |
| 背景介绍 | This gene encodes an enzyme that has E2-dependent E3 ubiquitin-protein ligase activity. This enzyme belongs to a class of ubiquitin ligases that include a RING finger motif, and it can interact with the E2 ubiquitin-conjugating enzyme UbcH5B. This gene is located in an area of chromosome X where several X-linked cognitive disability disorders have been associated, and it has also been found as part of a contiguous gene deletion associated with craniofrontonasal syndrome, though a direct link to any disorder has yet to be demonstrated. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
| 生物功能 | Has E2-dependent E3 ubiquitin-protein ligase activity. Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome. May be involved in protein sorting. [Uniprot] |
| 预测分子量 | 71 kDa |
| 翻译后修饰 | Phosphoprotein, Ubl conjugation. [Uniprot] |
检测图片 (1) Click the Picture to Zoom In
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ARG44892 anti-PJA1 antibody IHC-P image
Immunohistochemistry: Human brain stained with ARG44892 anti-PJA1 antibody at 5 µg/mL dilution.
