ARG43974
anti-PRPF19 antibody
anti-PRPF19 antibody for ELISA,Flow cytometry,ICC/IF,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PRPF19 |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PRPF19 |
| 抗原物种 | Human |
| 抗原 | Human PRPF19 recombinant protein |
| 表达系统 | E.coli |
| 偶联标记 | Un-conjugated |
| Protein Full name | Pre-mRNA-processing factor 19 |
| 別名 | PRPF19; Pre-MRNA Processing Factor 19; NMP200; SNEV; UBOX4; HPSO4; PRP19; PSO4; Nuclear Matrix Protein NMP200 Related To Splicing Factor PRP19; RING-Type E3 Ubiquitin Transferase PRP19; Pre-MRNA-Processing Factor 19; Nuclear Matrix Protein 200; Senescence Evasion Factor; PRP19/PSO4 Homolog; Psoralen 4; PRP19/PSO4 Pre-MRNA Processing Factor 19 Homolog (S. Cerevisiae) ; PRP19/PSO4 Homolog (S. Cerevisiae); EC 2.3.2.27; HPso4 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PRPF19 |
| 全名 | Pre-MRNA Processing Factor 1 |
| 背景介绍 | Enables identical protein binding activity and ubiquitin-ubiquitin ligase activity. Involved in several processes, including DNA damage checkpoint signaling; cellular protein metabolic process; and mRNA splicing, via spliceosome. Acts upstream of or within protein polyubiquitination. Located in cytoplasm; nuclear speck; and site of double-strand break. Part of Prp19 complex and U2-type catalytic step 2 spliceosome. Colocalizes with DNA replication factor A complex. |
| 生物功能 | Ubiquitin-protein ligase which is a core component of several complexes mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome. |
| 细胞定位 | Cytoplasm, Cytoskeleton, Lipid droplet, Nucleus, Spliceosome |
| 预测分子量 | 55 kDa |
| 翻译后修饰 | Acetylation |
检测图片 (3) Click the Picture to Zoom In
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ARG43974 anti-PRPF19 antibody WB image
Western blot: Jurkat and A431 stained withARG43974 anti-PRPF19 antibody at 0.5 μg/mL dilution.
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ARG43974 anti-PRPF19 antibody ICC/IF image
Immunofluorescence: A549 cells stained with ARG43974 anti-PRPF19 antibody antibody at 5 μg/ml dilution.
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ARG43974 anti-PRPF19 antibody FACS image
Flow Cytometry: JK cells stained with ARG43974 anti-PRPF19 antibody (blue) at 1 μg/1x10^6 cells dilution.
