ARG10420

anti-PSA antibody [8A6]

anti-PSA antibody [8A6] for ELISA and Human

Cancer antibody; Controls and Markers antibody; Neuroscience antibody; Signaling Transduction antibody

概述

产品描述 Mouse Monoclonal antibody [8A6] recognizes PSA
反应物种 Hu
应用 ELISA
宿主 Mouse
克隆 Monoclonal
克隆号 8A6
同位型 IgG2a
靶点名称 PSA
抗原物种 Human
抗原 human PSA antigen purified from seminal plasma
偶联标记 Un-conjugated
別名 Prostate-specific antigen; Gamma-seminoprotein; APS; PSA; EC 3.4.21.77; Kallikrein-3; P-30 antigen; Semenogelase; hK3; Seminin; KLK2A1

应用说明

应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Protein A affinity purified.
缓冲液 PBS (pH 7.4) and 0.1% Sodium azide
抗菌剂 0.1% Sodium azide
浓度 1.0-2.0 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 354 Human KLK3

Swiss-port # P07288 Human Prostate-specific antigen

基因名称 KLK3
全名 kallikrein-related peptidase 3
背景介绍 Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
生物功能 Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum. [UniProt]
研究领域 Cancer antibody; Controls and Markers antibody; Neuroscience antibody; Signaling Transduction antibody
预测分子量 29 kDa

克隆号文献

Development of simultaneous detection of total prostate-specific antigen (tPSA) and free PSA with rapid bead-based immunoassay.

Xie C et al.
J Clin Lab Anal.,  (2011)

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Simultaneous detection of free and total prostate specific antigen on a screen-printed electrochemical dual sensor.

Escamilla-Gómez V et al.
Biosens Bioelectron.,  (2009)

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