ARG44000
anti-PSMD7 antibody
anti-PSMD7 antibody for ELISA,Flow cytometry,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PSMD7 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ELISA, FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PSMD7 |
| 抗原物种 | Human |
| 抗原 | Human PSMD7 recombinant protein |
| 表达系统 | E.coli |
| 偶联标记 | Un-conjugated |
| Protein Full name | 26S proteasome non-ATPase regulatory subunit 7 |
| 別名 | PSMD7; Proteasome 26S Subunit, Non-ATPase 7; MOV34; Rpn8; S12; P40; Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 7 (Mov34 Homolog); 26S Proteasome Non-ATPase Regulatory Subunit 7; 26S Proteasome Regulatory Subunit S12; Proteasome Subunit P40; Mov34 Homolog; Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 7; Moloney Leukemia Virus-34 Proviral Integration; 26S Proteasome Regulatory Subunit Rpn8; 26S Proteasome Regulatory Subunit RPN8; Mov34 Protein Homolog; MOV34L |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P26516 Mouse 26S proteasome non-ATPase regulatory subunit 7 Swiss-port # P51665 Human 26S proteasome non-ATPase regulatory subunit 7 |
|---|---|
| 基因名称 | PSMD7 |
| 全名 | Proteasome 26S Subunit, Non-ATPase 7 |
| 背景介绍 | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17. |
| 生物功能 | Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. |
| 细胞定位 | Proteasome |
| 预测分子量 | 37 kDa |
| 翻译后修饰 | Acetylation, Isopeptide bond, Ubl conjugation |
检测图片 (4) Click the Picture to Zoom In
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ARG44000 anti-PSMD7 antibody WB image
Western blot: Hela and K562 stained with ARG44000 anti-PSMD7 antibody at 0.5 μg/mL dilution.
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ARG44000 anti-PSMD7 antibody WB image FACS image
Flow Cytometry: MCF-7 cells stained with ARG44000 anti-PSMD7 antibody WB image (blue) at 1 μg/1x10^6 cells dilution.
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ARG44000 anti-PSMD7 antibody WB image
Western blot: Rat liver and RH35 stained with ARG44000 anti-PSMD7 antibody at 0.5 μg/mL dilution.
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ARG44000 anti-PSMD7 antibody WB image
Western blot: Mouse liver and NIH/3T3 stained with ARG44000 anti-PSMD7 antibody at 0.5 μg/mL dilution.
