ARG56299
anti-PSMD7 antibody
anti-PSMD7 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
产品描述 | Rabbit Polyclonal antibody recognizes PSMD7 |
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反应物种 | Hu, Ms |
应用 | ICC/IF, IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | PSMD7 |
抗原物种 | Human |
抗原 | Recombinant protein of Human PSMD7 |
偶联标记 | Un-conjugated |
別名 | 26S proteasome regulatory subunit RPN8; Rpn8; S12; Proteasome subunit p40; Mov34 protein homolog; 26S proteasome non-ATPase regulatory subunit 7; MOV34; 26S proteasome regulatory subunit S12; P40 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
阳性对照 | SW620 |
属性
形式 | Liquid |
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纯化 | Affinity purification with immunogen. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 |
Swiss-port # P26516 Mouse 26S proteasome non-ATPase regulatory subunit 7 Swiss-port # P51665 Human 26S proteasome non-ATPase regulatory subunit 7 |
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基因名称 | PSMD7 |
全名 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 |
背景介绍 | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2008] |
生物功能 | Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. [UniProt] |
预测分子量 | 37 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG56299 anti-PSMD7 antibody ICC/IF image
Immunofluorescence: U2OS cells stained with ARG56299 anti-PSMD7 antibody.
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ARG56299 anti-PSMD7 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse spleen stained with ARG56299 anti-PSMD7 antibody at 1:100 dilution.
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ARG56299 anti-PSMD7 antibody WB image
Western blot: SW620 cell lysate stained with ARG56299 anti-PSMD7 antibody.