ARG66676
anti-Placental Lactogen antibody [SQab19161]
anti-Placental Lactogen antibody [SQab19161] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Recombinant Rabbit Monoclonal antibody [SQab19161] recognizes Placental Lactogen |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab19161 |
| 同位型 | IgG |
| 靶点名称 | Placental Lactogen |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide within aa. 100-200 of Human Placental Lactogen. |
| 偶联标记 | Un-conjugated |
| 別名 | Choriomammotropin; hCS-A; Lactogen; Placental lactogen; CSA; Chorionic somatomammotropin hormone 1; hCS-1; CSMT; CS-1; PL |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P0DML2 Human Chorionic somatomammotropin hormone 1 |
|---|---|
| 基因名称 | CSH1 |
| 全名 | chorionic somatomammotropin hormone 1 (placental lactogen) |
| 背景介绍 | The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq, Jul 2008] |
| 生物功能 | Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 25 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG66676 anti-Placental Lactogen antibody [SQab19161] IHC-P image
Immunohistochemistry: Paraffin-embedded Human endometrial cancer tissue stained with ARG66676 anti-Placental Lactogen antibody [SQab19161].
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ARG66676 anti-Placental Lactogen antibody [SQab19161] IHC-P image
Immunohistochemistry: Formalin/PFA-fixed and paraffin-embedded Human placenta tissue stained with ARG66676 anti-Placental Lactogen antibody [SQab19161]. Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0).
