ARG57942
anti-Properdin antibody
anti-Properdin antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Properdin |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Properdin |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 190-469 of Human Properdin (NP_001138724.1). |
| 偶联标记 | Un-conjugated |
| 別名 | PFC; PFD; BFD; PROPERDIN; Complement factor P; Properdin |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | 3T3L1 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CFP |
| 全名 | complement factor properdin |
| 背景介绍 | This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Feb 2009] |
| 生物功能 | A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 51 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG57942 anti-Properdin antibody ICC/IF image
Immunofluorescence: U2OS cells stained with ARG57942 anti-Properdin antibody.
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ARG57942 anti-Properdin antibody WB image
Western blot: 25 µg of 3T3L1 cell lysate stained with ARG57942 anti-Properdin antibody at 1:1000 dilution.
