ARG43922
anti-RAGE antibody
anti-RAGE antibody for Western blot and Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes RAGE |
|---|---|
| 反应物种 | Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RAGE |
| 抗原物种 | Mouse |
| 抗原 | Mouse RAGE recombinant protein |
| 表达系统 | E.coli |
| 偶联标记 | Un-conjugated |
| Protein Full name | Advanced glycosylation end product-specific receptor |
| 別名 | AGER; Advanced Glycosylation End-Product Specific Receptor; RAGE; SCARJ1; SRAGE; Advanced Glycosylation End Product-Specific Receptor; Receptor For Advanced Glycation End-Products; Receptor For Advanced Glycosylation End Products |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | AGER |
|---|---|
| 全名 | Advanced Glycosylation End-Product Specific Receptor |
| 背景介绍 | The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene. |
| 生物功能 | Cell surface pattern recognition receptor that senses endogenous stress signals with a broad ligand repertoire including advanced glycation end products, S100 proteins, high-mobility group box 1 protein/HMGB1, amyloid beta/APP oligomers, nucleic acids, phospholipids and glycosaminoglycans. |
| 细胞定位 | Cell membrane, Membrane, Secreted |
| 预测分子量 | 43 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Phosphoprotein, Ubl conjugation |
检测图片 (1) Click the Picture to Zoom In
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ARG43922 anti-RAGE antibody WB image
Western blot: Rat lung and Mouse lung stained with ARG43922 anti-RAGE antibody at 0.5 μg/mL dilution.
