ARG64109
anti-RNF213 / C17orf 27 antibody
anti-RNF213 / C17orf 27 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Cell Biology and Cellular Response antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes RNF213 / C17orf 27 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RNF213 / C17orf 27 |
| 抗原物种 | Human |
| 抗原 | C-KTAAVLKWNRE |
| 偶联标记 | Un-conjugated |
| 別名 | MYMY2; EC 6.3.2.-; NET57; E3 ubiquitin-protein ligase RNF213; ALK lymphoma oligomerization partner on chromosome 17; KIAA1618; RING finger protein 213; Mysterin; ALO17; MYSTR; C17orf27 |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q63HN8 Human E3 ubiquitin-protein ligase RNF213 |
|---|---|
| 背景介绍 | This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2;17)(p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8;17)(q24;q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011] |
| 研究领域 | Cell Biology and Cellular Response antibody |
| 预测分子量 | 591 kDa |
| 翻译后修饰 | Autoubiquitinated. |
检测图片 (1) Click the Picture to Zoom In
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ARG64109 anti-RNF213 / C17orf 27 antibody IHC-P image
Immunohistochemistry: Paraffin embedded Human kidney. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG64109 anti-RNF213 / C17orf 27 antibody at 2.5 µg/ml dilution followed by AP-staining.
