ARG44923
anti-RNF6 antibody
anti-RNF6 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes RNF6 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | RNF6 |
| 抗原物种 | Human |
| 抗原表位 | FGELSSLMEA DSESELQRNG QHLPDMHSEL SNLGTDNNRS QHREGSSQDR QAQGDSTEMH GENETTQPHT RNSDSRGGRQ LRNPNNLVET GTLPILRLAH FFLLNESDDD DRIRGLTKEQ IDNLSTRHYE HNSIDSELGK |
| 偶联标记 | Un-conjugated |
| 別名 | RNF6; Ring Finger Protein 6; Ring Finger Protein (C3H2C3 Type) 6; E3 Ubiquitin-Protein Ligase RNF6; RING-H2 Protein RNF-6; DKFZp686P0776; RING-Type E3 Ubiquitin Transferase RNF6; EC 2.3.2.27; SPG2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | RNF6 |
| 全名 | Ring Finger Protein 6 |
| 背景介绍 | The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed. [provided by RefSeq, Jul 2008] |
| 生物功能 | May also bind DNA and function as a transcriptional regulator. Mediates polyubiquitination of QKI in macrophages, leading to its degradation. [UniProt] |
| 细胞定位 | Cell projection, Cytoplasm, Nucleus. [UniProt] |
| 预测分子量 | 78 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG44923 anti-RNF6 antibody IHC-P image
Immunohistochemistry: Human testis stained with ARG44923 anti-RNF6 antibody at 5 µg/mL dilution.
