ARG59513
anti-S100A11 antibody
anti-S100A11 antibody for ICC/IF,Immunoprecipitation,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes S100A11 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | S100A11 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-105 of Human S100A11 (NP_005611.1). |
| 偶联标记 | Un-conjugated |
| 別名 | S100 calcium-binding protein A11; MLN70; MLN 70; Protein S100-C; HEL-S-43; Metastatic lymph node gene 70 protein; Protein S100-A11; S100C; Calgizzarin |
应用说明
| 预测反应性说明 | Mouse, Rat | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | BxPC3 and 22RV1 | ||||||||
| 实际分子量 | 12 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | S100A11 |
| 全名 | S100 calcium binding protein A11 |
| 背景介绍 | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. [provided by RefSeq, Jul 2008] |
| 生物功能 | Facilitates the differentiation and the cornification of keratinocytes. [UniProt] |
| 细胞定位 | Cytoplasm. Nucleus. [UniProt] |
| 预测分子量 | 12 kDa |
| 翻译后修饰 | Phosphorylation at Thr-10 by PRKCA significantly suppresses homodimerization and promotes association with NCL/nucleolin which induces nuclear translocation. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG59513 anti-S100A11 antibody ICC/IF image
Immunofluorescence: U2OS cells stained with ARG59513 anti-S100A11 antibody.
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ARG59513 anti-S100A11 antibody WB image
Western blot: 25 µg of BxPC3 and 22RV1 cell lysates stained with ARG59513 anti-S100A11 antibody at 1:1000 dilution.
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ARG59513 anti-S100A11 antibody WB image
Western blot: 25 µg of extracts from normal (control) and S100A11 knockout (KO) HeLa cells, using ARG59513 anti-S100A11 antibody at 1:1000 dilution.
