ARG45264

anti-SCO1 antibody

anti-SCO1 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

概述

产品描述 Polyclonal antibody recognizes SCO1
反应物种 Hu
应用 FACS, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 SCO1
抗原物种 Human
抗原 Recombinant protein containing to human SCO1.
偶联标记 Un-conjugated
別名 SCO1; Synthesis Of Cytochrome C Oxidase 1; SCOD1; SCO1, Cytochrome C Oxidase Assembly Protein; SCO Cytochrome C Oxidase Assembly Protein 1; Protein SCO1 Homolog, Mitochondrial; SCO (Cytochrome Oxidase Deficient, Yeast) Homolog 1; SCO Cytochrome Oxidase Deficient Homolog 1 (Yeast); SCO Cytochrome Oxidase Deficient Homolog 1; MC4DN4

应用说明

应用建议
应用 推荐稀释比
FACS1 - 3 µg/10^6 cells
IHC-P2-5 μg/ml
WB0.25-0.5 μg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量 30 kDa

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
稳定剂 4% Trehalose
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 6341 Human SCO1

Swiss-port # O75880 Human Protein SCO1 homolog, mitochondrial

基因名称 SCO1
全名 Synthesis Of Cytochrome C Oxidase 1
背景介绍 Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. In yeast, 2 related COX assembly genes, SCO1 and SCO2 (synthesis of cytochrome c oxidase), enable subunits 1 and 2 to be incorporated into the holoprotein. This gene is the human homolog to the yeast SCO1 gene. [provided by RefSeq, Jul 2008]
生物功能 Copper metallochaperone essential for the maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Not required for the synthesis of MT-CO2/COX2 but plays a crucial role in stabilizing MT-CO2/COX2 during its subsequent maturation. Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. [UniProt]
细胞定位 Membrane; Mitochondrion; Mitochondrion inner membrane. [UniProt]
预测分子量 34 kDa
翻译后修饰 Disulfide bond. [UniProt]

检测图片 (3) Click the Picture to Zoom In

  • ARG45264 anti-SCO1 antibody IHC-P image

    Immunohistochemistry: Human thyroid cancer stained with ARG45264 anti-SCO1 antibody at 2 μg/ml dilution.

  • ARG45264 anti-SCO1 antibody WB image

    Western blot: Daudi and 293T stained with ARG45264 anti-SCO1 antibody at 0.5 μg/ml dilution.

  • ARG45264 anti-SCO1 antibody FACS image

    Flow Cytometry: U87 stained with ARG45264 anti-SCO1 antibody at 1 µg/10^6 cells dilution.