ARG44318
anti-SHPRH antibody
anti-SHPRH antibody for Western blot and Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SHPRH |
|---|---|
| 反应物种 | Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SHPRH |
| 抗原物种 | Mouse |
| 抗原 | Synthetic peptide |
| 偶联标记 | Un-conjugated |
| 別名 | SHPRH; SNF2 Histone Linker PHD RING Helicase; BA545I5.2; KIAA2023; SNF2, Histone-Linker, PHD And RING Finger Domain-Containing Helicase; SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase; RING-Type E3 Ubiquitin Transferase SHPRH; E3 Ubiquitin-Protein Ligase SHPRH; FLJ90837 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Antigen Affinity Purified |
| 缓冲液 | PBS with 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SHPRH |
| 全名 | SNF2 Histone Linker PHD RING Helicase |
| 背景介绍 | SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases. SHPRH is a functional homolog of S. cerevisiae RAD5. |
| 生物功能 | E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'. |
| 预测分子量 | 193 kDa |
| 翻译后修饰 | Phosphoprotein |
