ARG67072
anti-StAR antibody [SQab30347]
anti-StAR antibody [SQab30347] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Recombinant Rabbit Monoclonal antibody [SQab30347] recognizes StAR |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab30347 |
| 同位型 | IgG |
| 靶点名称 | StAR |
| 抗原物种 | Human |
| 抗原 | Recombinant protein fragment of StAR |
| 偶联标记 | Un-conjugated |
| Protein Full name | StAR |
| 別名 | STAR; Steroidogenic Acute Regulatory Protein; STARD1; StAR Related Lipid Transfer (START) Domain Containing 1; Steroidogenic Acute Regulatory Protein, Mitochondrial; START Domain-Containing Protein 1; Steroidogenic Acute Regulator; Testis Secretory Sperm-Binding Protein Li 241mP; Mitochondrial Steroid Acute Regulatory Protein; Steroid Acute Regulatory Protein; START Domain Containing 1; Cholesterol Trafficker; StARD1; StAR |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P49675 Human Steroidogenic acute regulatory protein, mitochondrial |
|---|---|
| 基因名称 | STAR |
| 全名 | steroidogenic acute regulatory protein |
| 背景介绍 | The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jul 2008] |
| 生物功能 | Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. [UniProt] |
| 细胞定位 | Mitochondrion. [UniProt] |
| 预测分子量 | 32 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG67072 anti-StAR antibody [SQab30347] IHC-P image
Immunohistochemistry: Human adrenocortical adenoma tissue stained with ARG67072 anti-StAR antibody [SQab30347] at 1:100 dilution.
