ARG63588
anti-TIF1A / TRIM24 antibody
anti-TIF1A / TRIM24 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Gene Regulation antibody; Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes TIF1A / TRIM24 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Cow |
| 应用 | IHC-P |
| 特异性 | This antibody is expected to recognise both reported isoforms, as represented by NP_003843.3 and NP_056989.2. |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TIF1A / TRIM24 |
| 抗原物种 | Human |
| 抗原 | C-KRLKSIEERQLLK |
| 偶联标记 | Un-conjugated |
| 別名 | RNF82; EC 6.3.2.-; Transcription intermediary factor 1-alpha; TIF1A; E3 ubiquitin-protein ligase TRIM24; RING finger protein 82; Tripartite motif-containing protein 24; TIF1-alpha; hTIF1; TF1A; TIF1ALPHA; TIF1; PTC6 |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O15164 Human Transcription intermediary factor 1-alpha |
|---|---|
| 背景介绍 | The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
| 研究领域 | Gene Regulation antibody; Signaling Transduction antibody |
| 预测分子量 | 117 kDa |
| 翻译后修饰 | Sumoylated. |
检测图片 (1) Click the Picture to Zoom In
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ARG63588 anti-TIF1A / TRIM24 antibody IHC-P image
Immunohistochemistry: paraffin embedded Human Breast cancer. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63588 anti-TIF1 alpha antibody at 4 µg/ml dilution followed by HRP-staining.
