ARG66106
anti-TL1A antibody
anti-TL1A antibody for ELISA and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes TL1A |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TL1A |
| 抗原物种 | Human |
| 抗原 | E. coli derived recombinant Human TL1A. (QLRAQGEASV QFQALKGQEF APSHQQVYAP LRADGDKPRA HLTVVRQTPT QHFKNQFPAL HWEHELGLAF TKNRMNYTNK FLLIPESGDY FIYSQVTFRG MTSECSEIRQ AGRPNKPDSI TVVITKVTDS YPEPTQLLMG TKSVCEVGSN WFQPIYLGAM FSLQEGDKLM VNVSDISLVD YTKEDKTFFG AFLL) |
| 偶联标记 | Un-conjugated |
| 別名 | TL1; Vascular endothelial cell growth inhibitor; TL1A; VEGI192A; TNF ligand-related molecule 1; VEGI; Tumor necrosis factor ligand superfamily member 15 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O95150 Human Tumor necrosis factor ligand superfamily member 15 |
|---|---|
| 基因名称 | TNFSF15 |
| 全名 | tumor necrosis factor (ligand) superfamily, member 15 |
| 背景介绍 | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011] |
| 生物功能 | Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. [UniProt] |
| 预测分子量 | 28 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG66106 anti-TL1A antibody standard curve image
Sandwich ELISA: ARG66106 anti-TL1A antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG66107 anti-TL1A antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density reading at 405 - 650 nm.
