概述

产品描述	Rabbit Polyclonal antibody recognizes TLR2
反应物种	Ms
应用	ELISA, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	TLR2
抗原物种	Mouse
抗原	Mouse TLR2 recombinant protein
表达系统	E.coli
偶联标记	Un-conjugated
Protein Full name	Toll-like receptor 2
別名	TLR2; Toll Like Receptor 2; TIL4; Toll-Like Receptor 2; CD282; Toll/Interleukin-1 Receptor-Like Protein 4; CD282 Antigen

应用说明

应用建议	应用 推荐稀释比 ELISA 0.1-0.5 µg/ml WB 0.25-0.5 µg/ml
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Affinity purified with Immunogen.
缓冲液	0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose.
稳定剂	4% Trehalose
浓度	0.5 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

基因名称	TLR2
全名	Toll Like Receptor 2
背景介绍	The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants.
生物功能	Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.
细胞定位	Cytoplasmic vesicle, Membrane
预测分子量	90 kDa
翻译后修饰	Disulfide bond, Glycoprotein, Isopeptide bond, Ubl conjugation

检测图片 (1) Click the Picture to Zoom In