ARG56104
anti-TNFRSF18 antibody [DTA-1]
anti-TNFRSF18 antibody [DTA-1] for Flow cytometry,ICC/IF and Mouse
概述
| 产品描述 | Rat Monoclonal antibody [DTA-1] recognizes TNFRSF18 |
|---|---|
| 反应物种 | Ms |
| 应用 | FACS, ICC/IF |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | DTA-1 |
| 同位型 | IgG2b, lambda |
| 靶点名称 | TNFRSF18 |
| 抗原物种 | Mouse |
| 抗原 | Mouse CD25+ CD4+ T cells. |
| 偶联标记 | Un-conjugated |
| 別名 | AITR; CD antigen CD357; Tumor necrosis factor receptor superfamily member 18; Glucocorticoid-induced TNFR-related protein; Gitr |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 0.1 mg/ml BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O35714 Mouse Tumor necrosis factor receptor superfamily member 18 |
|---|---|
| 基因名称 | Tnfrsf18 |
| 全名 | tumor necrosis factor receptor superfamily, member 18 |
| 背景介绍 | This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011] |
| 生物功能 | Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway (By similarity). [UniProt] |
| 细胞定位 | Secreted, cell surface |
| 预测分子量 | 26 kDa |
