ARG44969
anti-TRIM65 antibody
anti-TRIM65 antibody for Immunoprecipitation,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes TRIM65 |
|---|---|
| 反应物种 | Hu |
| 应用 | IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2b |
| 靶点名称 | TRIM65 |
| 抗原物种 | Human |
| 抗原表位 | DAERLKREAQ LRASLEVTQQ QATQAEGQLL ELRKQSSQIQ NSACILASWV SGKFSSLLQA LEIQHTTALR SIEVAKTQAL AQARDEEQRL RVHLEAVARH GCRIRELLEQ VDEQTFLQES QLLQPPGPLG PLTPLQWDED QQLGDLKQLL SRLCGLLLEE GSHPGAPAKP VDLAPVEAPG |
| 偶联标记 | Un-conjugated |
| 別名 | TRIM65; Tripartite Motif Containing 65; Tripartite Motif-Containing Protein 65; E3 Ubiquitin-Protein Ligase TRIM65; Tripartite Motif-Containing 65; 4732463G12Rik; EC 2.3.2.27 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q6PJ69 Human Tripartite motif-containing protein 65 |
|---|---|
| 基因名称 | TRIM65 |
| 全名 | Tripartite Motif Containing 65 |
| 背景介绍 | Predicted to enable zinc ion binding activity. Involved in positive regulation of autophagy. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] |
| 生物功能 | In addition, negatively regulates inflammasome activation by promoting 'lys48'-linked ubiquitination of NLRP3 which is critical for the inhibition of NLRP3 inflammasome activation in resting macrophages. [Uniprot] |
| 细胞定位 | Cytoplasm. [Uniprot] |
| 翻译后修饰 | Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation. [Uniprot] |
检测图片 (2) Click the Picture to Zoom In
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ARG44969 anti-TRIM65 antibody WB image
Western blot: K562 stained with ARG44969 anti-TRIM65 antibody at 1 µg/mL dilution.
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ARG44969 anti-TRIM65 antibody IP image
Immunoprecipitation: K562 lysate immunoprecipitated with 2.5 µg of ARG44969 anti-TRIM65 antibody.
