概述

产品描述	Rabbit Polyclonal antibody recognizes TRP1
反应物种	Hu
应用	IHC-P, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	TRP1
抗原物种	Human
抗原	Synthetic peptide derived from Human TRP1.
偶联标记	Un-conjugated
別名	CATB; TYRP; b-PROTEIN; EC 1.14.18.-; CAS2; DHICA oxidase; Melanoma antigen gp75; 5,6-dihydroxyindole-2-carboxylic acid oxidase; Catalase B; OCA3; TRP; GP75; TRP1; Glycoprotein 75; TRP-1; Tyrosinase-related protein 1

应用说明

应用建议	应用 推荐稀释比 IHC-P 1:50 - 1:200 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量	~ 75 kDa

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 7306 Human TYRP1 Swiss-port # P17643 Human 5,6-dihydroxyindole-2-carboxylic acid oxidase
基因名称	TYRP1
全名	tyrosinase-related protein 1
背景介绍	This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. [provided by RefSeq, Mar 2009]
生物功能	Oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized. [UniProt]
细胞定位	Melanosome membrane; Single-pass type I membrane protein. Melanosome. Note=Located to mature stage III and IV melanosomes and apposed endosomal tubular membranes. Transported to pigmented melanosomes by the BLOC-1 complex. Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38. [UniProt]
预测分子量	61 kDa
翻译后修饰	Glycosylated. [UniProt]

检测图片 (1) Click the Picture to Zoom In