ARG59403
anti-TSHR / TSH Receptor antibody
anti-TSHR / TSH Receptor antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes TSHR / TSH Receptor |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TSHR / TSH Receptor |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 21-253 of Human TSHR (NP_001018046.1). |
| 偶联标记 | Un-conjugated |
| 別名 | LGR3; TSH-R; CHNG1; Thyrotropin receptor; Thyroid-stimulating hormone receptor; hTSHR-I |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse eye | ||||||
| 实际分子量 | ~ 110 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TSHR |
| 全名 | thyroid stimulating hormone receptor |
| 背景介绍 | The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] |
| 生物功能 | Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5). [UniProt] |
| 预测分子量 | 87 kDa |
| 翻译后修饰 | Glycosylated. Sulfated. Sulfation on Tyr-385 plays a role in thyrotropin receptor binding and activation. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG59403 anti-TSHR / TSH Receptor antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat brain stained with ARG59403 anti-TSHR / TSH Receptor antibody at 1:100 dilution.
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ARG59403 anti-TSHR / TSH Receptor antibody WB image
Western blot: 25 µg of Mouse eye lysate stained with ARG59403 anti-TSHR / TSH Receptor antibody at 1:1000 dilution.
