ARG63113
anti-Thyroglobulin antibody [TSH-116]
anti-Thyroglobulin antibody [TSH-116] for ELISA,Radioimmunoassay and Human
Cancer antibody; Signaling Transduction antibody
概述
| 产品描述 | Mouse Monoclonal antibody [TSH-116] recognizes Thyroglobulin |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, RIA |
| 特异性 | The clone TSH-116 reacts with human thyroid stimulating hormone (hTSH, thyrotropin), a glycoprotein hormone produced by the anterior pituitary gland cells in response to signals from the hypothalamus gland in the brain. The TSH-116 reacts with association constant 1.1 x 1011 l/mol. Following cross-reactivity expressed as binding of labelled hormone (% of total) was determined by solid phase RIA with excess of the antibody TSH-116: hTSH (78.9), hCG (20.3), hLH (23.2), hFSH (29.9). |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | TSH-116 |
| 同位型 | IgG2a |
| 靶点名称 | Thyroglobulin |
| 抗原物种 | Human |
| 抗原 | Human thyrotropin. |
| 偶联标记 | Un-conjugated |
| 別名 | AITD3; Tg; TGN; Thyroglobulin |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | RIA: The clone TSH-116 is suitable in combination with the clone TSH-51 (ARG63112) for immunometric assays in the screening of neonatal hypothyroidism. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from ascites by protein-A affinity chromatography. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TG |
| 全名 | thyroglobulin |
| 背景介绍 | Thyrotropin (hTSH) promotes the growth of the thyroid gland in the neck and stimulates it to produce more thyroid hormones. hTSH is composed of two subunits - alpha nad beta. |
| 生物功能 | Precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). [UniProt] |
| 研究领域 | Cancer antibody; Signaling Transduction antibody |
| 预测分子量 | 305 kDa |
| 翻译后修饰 | Sulfated tyrosines are desulfated during iodination. |
