概述

产品描述	Rabbit Polyclonal antibody recognizes UBA6
反应物种	Hu
预测物种	Ms
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	UBA6
抗原物种	Human
抗原	KLH-conjugated synthetic peptide corresponding to aa. 861-889 of Human UBA6.
偶联标记	Un-conjugated
別名	E1-L2; MOP-4; Ubiquitin-activating enzyme 6; Ubiquitin-like modifier-activating enzyme 6; Ubiquitin-activating enzyme E1-like protein 2; UBE1L2; Monocyte protein 4

应用说明

应用建议	应用 推荐稀释比 WB 1:1000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	K562

属性

形式	Liquid
纯化	Purification with Protein A and immunogen peptide.
缓冲液	PBS and 0.09% (W/V) Sodium azide.
抗菌剂	0.09% (W/V) Sodium azide.
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 55236 Human UBA6 Swiss-port # A0AVT1 Human Ubiquitin-like modifier-activating enzyme 6
基因名称	UBA6
全名	ubiquitin-like modifier activating enzyme 6
背景介绍	Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al., 2007 [PubMed 17597759]).[supplied by OMIM, Mar 2008]
生物功能	Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Specific for ubiquitin, does not activate ubiquitin-like peptides. Differs from UBE1 in its specificity for substrate E2 charging. Does not charge cell cycle E2s, such as CDC34. Essential for embryonic development. Required for UBD/FAT10 conjugation. Isoform 2 may play a key role in ubiquitin system and may influence spermatogenesis and male fertility. [UniProt]
预测分子量	118 kDa

检测图片 (1) Click the Picture to Zoom In