ARG45445
anti-UBA6 antibody
anti-UBA6 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Monkey,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes UBA6 |
|---|---|
| 反应物种 | Hu, Ms, Rat, Mk |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | UBA6 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human UBA6. |
| 偶联标记 | Un-conjugated |
| 別名 | UBA6; Ubiquitin Like Modifier Activating Enzyme 6; UBE1L2; Ubiquitin-Activating Enzyme E1-Like Protein 2; Ubiquitin-Like Modifier-Activating Enzyme 6; Ubiquitin-Activating Enzyme E1-Like 2; UBA6, Ubiquitin-Activating Enzyme E1; Ubiquitin-Activating Enzyme 6; Monocyte Protein 4; FLJ10808; E1-L2; MOP-4; Ubiquitin-Like Modifier Activating Enzyme 6; EC 6.2.1.45; MOP4 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 118 kDa |
属性
| 形式 | Powder |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # A0AVT1 Human Ubiquitin-like modifier-activating enzyme 6 Swiss-port # Q8C7R4 Mouse Ubiquitin-like modifier-activating enzyme 6 |
|---|---|
| 基因名称 | UBA6 |
| 全名 | Ubiquitin Like Modifier Activating Enzyme 6 |
| 背景介绍 | Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al., 2007 [PubMed 17597759]).[supplied by OMIM, Mar 2008] |
| 生物功能 | Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Specific for ubiquitin, does not activate ubiquitin-like peptides. Differs from UBE1 in its specificity for substrate E2 charging. Does not charge cell cycle E2s, such as CDC34. Essential for embryonic development. Required for UBD/FAT10 conjugation. Isoform 2 may play a key role in ubiquitin system and may influence spermatogenesis and male fertility. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 118 kDa |
| 翻译后修饰 | Acetylation; Phosphoprotein. [UniProt] |
检测图片 (6) Click the Picture to Zoom In
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ARG45445 anti-UBA6 antibody IHC-P image
Immunohistochemistry: Human cervical cancer stained with ARG45445 anti-UBA6 antibody at 2 μg/ml dilution.
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ARG45445 anti-UBA6 antibody WB image
Western blot: MOLT-4 stained with ARG45445 anti-UBA6 antibody at 0.5 μg/ml dilution.
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ARG45445 anti-UBA6 antibody FACS image
Flow Cytometry: PC-3 stained with ARG45445 anti-UBA6 antibody at 1 µg/10^6 cells dilution.
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ARG45445 anti-UBA6 antibody WB image
Western blot: C6 stained with ARG45445 anti-UBA6 antibody at 0.5 μg/ml dilution.
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ARG45445 anti-UBA6 antibody WB image
Western blot: NIH/3T3 stained with ARG45445 anti-UBA6 antibody at 0.5 μg/ml dilution.
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ARG45445 anti-UBA6 antibody WB image
Western blot: COS-7 stained with ARG45445 anti-UBA6 antibody at 0.5 μg/ml dilution.
