ARG55541
anti-USP22 antibody
anti-USP22 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Cell Biology and Cellular Response antibody; Gene Regulation antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes USP22 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Bov, Xenopus, Zfsh |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | USP22 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 351-380 (C-terminus) of Human USP22. |
| 偶联标记 | Un-conjugated |
| 別名 | Ubiquitin carboxyl-terminal hydrolase 22; Ubiquitin-specific-processing protease 22; USP3L; Deubiquitinating enzyme 22; Ubiquitin thioesterase 22; EC 3.4.19.12 |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | HepG2 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9UPT9 Human Ubiquitin carboxyl-terminal hydrolase 22 |
|---|---|
| 基因名称 | USP22 |
| 全名 | ubiquitin specific peptidase 22 |
| 生物功能 | Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression. [UniProt] |
| 细胞定位 | Nucleus. |
| 研究领域 | Cell Biology and Cellular Response antibody; Gene Regulation antibody |
| 预测分子量 | 60 kDa |
检测图片 (2) Click the Picture to Zoom In
-
ARG55541 anti-USP22 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human cancer tissue stained with ARG55541 anti-USP22 antibody.
-
ARG55541 anti-USP22 antibody WB image
Western blot: 20 µg of HepG2 cell lysate stained with ARG55541 anti-USP22 antibody at 1:1000 dilution.
