ARG66937
anti-Uroplakin III antibody [SQab22267]
anti-Uroplakin III antibody [SQab22267] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Recombinant Rabbit Monoclonal antibody [SQab22267] recognizes Uroplakin III |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab22267 |
| 同位型 | IgG |
| 靶点名称 | Uroplakin III |
| 抗原物种 | Human |
| 抗原 | Full length protein corresponding to Human Uroplakin III. |
| 偶联标记 | Un-conjugated |
| Protein Full name | Uroplakin-3a |
| 別名 | UPIII; UPK3; Uroplakin-3a; UPIIIA; Uroplakin III; UP3A; UP3a |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0). Incubate the samples at RT (18-25°C) for 30 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 阳性对照 | Human urothelial carcinoma tissue |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05%BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | UPK3A |
| 全名 | uroplakin 3A |
| 背景介绍 | This gene encodes a member of the uroplakin family, a group of transmembrane proteins that form complexes on the apical surface of the bladder epithelium. Mutations in this gene may be associated with renal adysplasia. Alternatively spliced transcript variants have been described.[provided by RefSeq, Nov 2009] |
| 生物功能 | Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity). [UniProt] |
| 预测分子量 | 31 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG66937 anti-Uroplakin III antibody [SQab22267] IHC-P image
Immunohistochemistry: Formalin/PFA-fixed and paraffin-embedded sections of Human urothelial carcinoma tissue stained with ARG66937 anti-Uroplakin III antibody [SQab22267]. Antigen Retrieval: Heat tissue section in Tris-EDTA buffer (pH 9.0).
