ARG45086
anti-WASHC1 antibody
anti-WASHC1 antibody for ICC/IF,Western blot and Human,Mouse,Rat,Chicken
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes WASHC1 |
|---|---|
| 反应物种 | Hu, Ms, Rat, Chk |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | WASHC1 |
| 抗原物种 | Human |
| 抗原 | WASH synthetic peptide (coupled to carrier protein) corresponds to amino acids in the C-terminal region of human WASH. This sequence is highly conserved in rat, mouse, and chicken WASH, and has low homology to other WASP family members. |
| 偶联标记 | Un-conjugated |
| 別名 | WASHC1; WASH Complex Subunit 1; WAS Protein Family Homolog 1; FAM39E; WASH1; Family With Sequence Similarity 39, Member E; CXYorf1-Like Protein On Chromosome 9; FLJ00038; Actin Nucleation Promoting Factor; FLJ00075 Protein; Protein FAM39E; WASH |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Antigen Affinity Purified. |
| 缓冲液 | PBS, 0.05% NaN3, 50% Glycerol and 0.1 % BSA. |
| 稳定剂 | 50% Glycerol and 0.1 % BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | WASHC1 |
| 全名 | WASH Complex Subunit 1 |
| 背景介绍 | Enables alpha-tubulin binding activity and ubiquitin protein ligase binding activity. Involved in several processes, including Arp2/3 complex-mediated actin nucleation; endosomal transport; and positive regulation of pseudopodium assembly. Located in early endosome. Part of WASH complex. Colocalizes with exocyst. [provided by Alliance of Genome Resources, Apr 2022] |
| 生物功能 | Involved in negative regulation of autophagy independently from its role in endosomal sorting by inhibiting BECN1 ubiquitination to inactivate PIK3C3/Vps34 activity. [Uniprot] |
| 细胞定位 | Cytoplasm, Cytoplasmic vesicle, Cytoskeleton, Endosome, Membrane. [Uniprot] |
| 预测分子量 | 50 kDa |
| 翻译后修饰 | Isopeptide bond, Ubl conjugation. [Uniprot] |
