ARG55738
anti-ZO1 antibody
anti-ZO1 antibody for ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat,Dog,Monkey
参考文献8
概述
| 产品描述 | Goat Polyclonal antibody recognizes ZO1 |
|---|---|
| 反应物种 | Hu, Ms, Rat, Dog, Mk |
| 应用 | ICC/IF, IHC-Fr, IHC-P, WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ZO1 |
| 抗原物种 | Human |
| 抗原 | Purified recombinant peptide around aa. 1580 (C-terminus) of Human ZO-1 |
| 偶联标记 | Un-conjugated |
| 別名 | Zonula occludens protein 1; Tight junction protein ZO-1; Tight junction protein 1; Zona occludens protein 1; ZO-1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.05% Sodium azide and 20% Glycerol |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 20% Glycerol |
| 浓度 | 3 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TJP1 |
| 全名 | tight junction protein 1 |
| 背景介绍 | This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
| 生物功能 | The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells. [UniProt] |
| 预测分子量 | 195 kDa |
| 翻译后修饰 | Phosphorylated. Dephosphorylated by PTPRJ. |
检测图片 (2) Click the Picture to Zoom In
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ARG55738 anti-ZO1 antibody WB image
Western blot: 50 µg of total protein (MDCK cell lysate) stained with ARG55738 anti-ZO1 antibody at 1:2500 dilution.
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ARG55738 anti-ZO1 antibody ICC/IF image
Immunocytochemistry: primary RPE cells stained with ARG55738 anti-ZO1 antibody at 1:100 dilution.
文献引用
Incomplete Recovery from the Radiocontrast-Induced Dysregulated Cell Cycle, Adhesion, and Fibrogenesis in Renal Tubular Cells after Radiocontrast (Iohexol) Removal
WB / Human
Intestinal epithelium-specific Fut2 deficiency promotes colorectal cancer through down-regulating fucosylation of MCAM
IHC-P / Mouse
MicroRNA-29b Suppresses Inflammation and Protects Blood-Brain Barrier Integrity in Ischemic Stroke
WB / Mouse
Long non-coding RNA H19 promotes leukocyte inflammation in ischemic stroke by targeting the miR-29b/C1QTNF6 axis
WB / Rat
Gut microbiota-mediated lysophosphatidylcholine generation promotes colitis in intestinal epithelium-specific Fut2 deficiency.
WB / Mouse
Probiotic mixtures with aerobic constituent promoted the recovery of multi-barriers in DSS-induced chronic colitis.
WB / Mouse
Hyperoside protects the blood-brain barrier from neurotoxicity of amyloid beta 1-42.
WB / Mouse
Catalpol provides a protective effect on fibrillary Aβ1-42 -induced barrierdisruption in an in vitro model of the blood-brain barrier.
WB / Rat
