ARG58071
anti-alpha 1 Antichymotrypsin antibody
anti-alpha 1 Antichymotrypsin antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes alpha 1 Antichymotrypsin |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | alpha 1 Antichymotrypsin |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 24-423 of Human alpha 1 Antichymotrypsin (NP_001076.2). |
| 偶联标记 | Un-conjugated |
| 別名 | GIG24; GIG25; Cell growth-inhibiting gene 24/25 protein; Alpha-1-antichymotrypsin; ACT; Serpin A3; AACT |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse testis | ||||||
| 实际分子量 | ~ 47 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SERPINA3 |
| 全名 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| 背景介绍 | The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008] |
| 生物功能 | Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 48 kDa |
| 翻译后修饰 | N- and O-glycosylated. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG58071 anti-alpha 1 Antichymotrypsin antibody IHC-P image
Immunohistochemistry: Human prostate cancer stained with ARG58071 anti-alpha 1 Antichymotrypsin antibody at 1:100 dilution.
