ARG55932
anti-alpha Fetoprotein antibody [C3]
anti-alpha Fetoprotein antibody [C3] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody [C3] recognizes alpha Fetoprotein |
|---|---|
| 反应物种 | Hu |
| 不反应物种 | Ms, Rat, Cat, Cow |
| 应用 | IHC-P |
| 特异性 | AFP antibody [C3] is highly specific and shows no cross-reaction with other oncofetal antigens or serum albumin. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | C3 |
| 同位型 | IgG2a, kappa |
| 靶点名称 | alpha Fetoprotein |
| 抗原物种 | Human |
| 抗原 | Alpha fetoprotein purified from serum of a hepatoma patient. |
| 偶联标记 | Un-conjugated |
| 別名 | Alpha-fetoprotein; HPAFP; FETA; Alpha-fetoglobulin; AFPD; Alpha-1-fetoprotein |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 0.1 mg/ml BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | AFP |
| 全名 | alpha-fetoprotein |
| 背景介绍 | This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008] |
| 生物功能 | Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. [UniProt] |
| 细胞定位 | Cytoplasmic |
| 预测分子量 | 69 kDa |
| 翻译后修饰 | Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence. Sulfated. |
检测图片 (1) Click the Picture to Zoom In
-
ARG55932 anti-alpha Fetoprotein antibody [C3] IHC-P image
Immunohistochemistry: Human fetal liver stained with ARG55932 anti-alpha Fetoprotein antibody [C3].
