ARG83580
arigoQIK® Human IL13 ELISA Development Kit
arigoQIK® Human IL13 ELISA Development 试剂盒 for ELISA and Human
概述
| 产品描述 | ARG83580 arigoQIK® Human IL13 ELISA Development Kit, includes Capture antibody, Detection antibody, Standard, and HRP-Streptavidin Solution. This ELISA Development Kit is designed for the development of sandwich ELISA to measure Human IL13 in Serum, plasma and cell culture supernatants. For other reagents required for arigoQIK® ELISA Development Kit, please refer ARG83524 Integral Reagent Kit (ELISA Development Kit) More about arigoQIK® : ● Optimized capture and detection antibody pairs ● Reduced incubation time and wash cycles ● 2-hour quicker than conventional ELISA process ● 5- and 15-plate packages available |
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| 反应物种 | Hu |
| 应用 | ELISA |
| 靶点名称 | IL13 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 3.9 pg/ml |
| 样品类型 | Serum, plasma and cell culture supernatants. |
| 标准范围 | 7.8 - 500 pg/ml |
| 样本量 | 50 μl |
| 精确 | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| 別名 | IL13; Interleukin 13; IL-13; P600; Interleukin-13; MGC116786; MGC116788; MGC116789; ALRH; BHR1; Bronchial Hyperresponsiveness-1 (Bronchial Asthma); Allergic Rhinitis; NC30 |
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store components at 4°C or -20°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IL13 |
| 全名 | Interleukin 13 |
| 背景介绍 | This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008] |
| 生物功能 | Exerts its biological effects through its receptors which comprises the IL4R chain and the IL13RA1 chain, to activate JAK1 and TYK2, leading to the activation of STAT6. Aside from IL13RA1, another receptor IL13RA2 acts as a high affinity decoy for IL13 and mediates internalization and depletion of extracellular IL13. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 翻译后修饰 | Disulfide bond, Glycoprotein. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG83580 arigoQIK Human IL13 ELISA Development Kit standard curve image
ARG83580 arigoQIK Human IL13 ELISA Development Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG83580 arigoQIKTM Human IL13 ELISA Development Kit User manual |
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