ARG30211

Phospho Tau Antibody Panel (Total, pS396, pS404)

Immune System antibody; Neuroscience antibody; Signaling Transduction antibody

内含物

货号 内含物名称 宿主克隆性 反应 应用 包装
ARG51614 anti-Tau phospho (Ser404) antibody Rabbit pAb Hu, Ms, Rat ICC/IF, IHC-P, WB 50 μl
ARG51604 anti-Tau phospho (Ser396) antibody Rabbit pAb Hu, Ms, Rat IHC-P, WB 50 μl
ARG51094 anti-Tau antibody Rabbit pAb Hu, Ms, Rat IHC-P, WB 50 μl
ARG65351 Goat anti-Rabbit IgG antibody (HRP) Goat pAb Rb ELISA, IHC-P, WB 50 μl

概述

产品描述 Tau is a group of neuronal microtubule-associated proteins that are formed by alternative mRNA splicing and accumulate in neurofibrillary tangles in Alzheimer's disease (AD) brain. Tau plays a key role in regulating microtubule dynamics, axonal transport and neurite outgrowth, and all these functions of tau are modulated by site-specific phosphorylation. Phosphorylation of Tau (Isoform Tau-F) at Ser296 and Ser404 sites by Tau Protein Kinase II is responsible for the functional loss of tau-mediated tubulin polymerization in AD. Evans et al. 2000. J Biol Chem 275(32): 24977-83 Stoothoff and Johnson. 2005. Biochem Biophy Acta 1739(2-3): 280-97
靶点名称 Tau
別名 Phospho Tau antibody; Tau antibody; Tau phospho (Ser396) antibody; Tau phospho (Ser404) antibody

属性

存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

全名 Antibody Panel for Phospho Tau (Total, pS396, pS404)
产品亮点 Related Product:
anti-Tau antibody;
研究领域 Immune System antibody; Neuroscience antibody; Signaling Transduction antibody

检测图片 (14) Click the Picture to Zoom In

  • ARG51094 anti-Tau antibody WB image

    Western blot: 30 µg of 1) Mouse brain and 2) Rat brain tissue lysate stained with ARG51094 anti-Tau antibody at 1:500 dilution.

  • ARG51604 anti-Tau phospho (Ser396) antibody WB image

    Western blot: 30 µg of 1) Mouse brain and 2) Rat brain tissue lysate stained with ARG51604 anti-Tau phospho (Ser396) antibody at 1:500 dilution.

  • ARG51614 anti-Tau phospho (Ser404) antibody WB image

    Western blot: 30 µg of Mouse brain and Rat brain tissue lysates stained with ARG51614 anti-Tau phospho (Ser404) antibody at 1:500 dilution.

  • ARG51094 anti-Tau antibody WB image

    Western Blot: extracts from mouse brain tissue stained with anti-Tau antibody ARG51094.

  • ARG51094 anti-Tau antibody IHC-P image

    Immunohistochemistry: paraffin-embedded rat hippocampal region tissue from a model with Alzheimer stained with anti-Tau antibody ARG51094

  • ARG51604 anti-Tau phospho (Ser396) Antibody WB image

    Western Blot: extracts from mouse brain tissue stained with anti-Hsp90 antibody [D7 alpha] ARG51604 and the same antibody preincubated with blocking peptide.

  • ARG51604 anti-Tau phospho (Ser396) Antibody IHC-P image

    Immunohistochemistry: paraffin-embedded rat hippocampal region tissue from a model with Alzheimer stained with anti-Hsp90 antibody [D7 alpha] ARG51604

  • ARG51614 anti-Tau phospho (Ser404) antibody WB image

    Western Blot: extracts from C6 cells, treated with calf intestinal phosphatase (CIP), stained with anti-Tau (phospho Ser404) antibody ARG51614.

  • ARG51614 anti-Tau phospho (Ser404) antibody IHC-P image

    Immunohistochemistry: paraffin-embedded rat hippocampal region tissue from a model with Alzheimer stained with anti-Tau (phospho Ser404) antibody ARG51614

  • ARG51614 anti-Tau phospho (Ser404) antibody ICC/IF image

    Immunofluorescence: methanol-fixed HeLa cells stained with anti-Tau (phospho Ser404) antibody ARG51614.

  • ARG51614 anti-Tau phospho (Ser404) antibody WB image

    Western Blot: extracts from C6 cells stained with anti-Tau (phospho Ser404) antibody ARG51614.

  • ARG65351 Goat anti-Rabbit IgG antibody (HRP) WB image

    Western blot: Rat placental stained with ARG57589 anti-MTNR1A antibody at 1:1000 dilution, ARG65351 Goat anti-Rabbit IgG antibody (HRP) at 1:5000 dilution.

    From Jinzhi Li et al. J Reprod Immunol. (2023), doi: 10.1016/j.jri.2023.104166, Fig. 2.B.

  • ARG65351 Goat anti-Rabbit IgG antibody (HRP) WB image

    Western blot: Mouse retina stained with ARG65693 anti-alpha Tubulin antibody and ARG65351 Goat anti-Rabbit IgG antibody (HRP)

    From Xiaoyuan Ye et al. Mol Ther Nucleic Acids. (2024), doi: 10.1016/j.omtn.2024.102209, Fig. 5.D.

  • ARG65351 Goat anti-Rabbit IgG antibody (HRP) IHC-P image

    From Yu-Qian Song et al. J Mol Med (Berl) (2022), doi: 10.1007/s00109-021-02165-0, Fig. 5.c.